A logical prediction is that compared with rats born to mothers fed a healthy diet, the hnf4a gene in rats born to mothers fed a protein poor diet would.

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The inactivation of tumor suppressor genes leads to tumor development by eliminating negative regulatory proteins.

In some cases, tumor suppressor proteins inhibit the same cellular regulatory pathways stimulated by the products of oncogenes. DNA wraps around histone proteins to form so-called beads on nucleosomes and thread-like structures (euchromatin). Some histones are wrapped in 30-nanometer fibers composed of nucleosomal sequences in their most compact form (heterochromatin). Chromosomal DNA is packed into minute nuclei with the help of histones. These are positively charged proteins that attach tightly to negatively charged DNA, forming complexes called nucleosomes. If the mother carries the mutated gene type, the offspring will display the mutated phenotype. - This statement is true. The gene is transcribed in the mother and the mRNA is delivered to the fertilized egg.

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